Neurology
- An abnormal peripheral blood smear and altered mental status
Therapeutic plasma exchange has greatly increased the survival rate in thrombotic thrombocytopenic purpura.
- Thrombotic thrombocytopenic purpura: The role of ADAMTS13
ADAMTS13 testing is useful in diagnosing this disease, guiding therapy, and predicting relapse.
- Anticoagulation in dental surgery: Is it rude to interrupt?
Anticoagulation should not be interrupted for dental surgery.
- Multiple linear subcutaneous nodules
A 34-year-old woman has an asymptomatic swelling on her foot that has been slowly growing for 15 years.
- Predicting is tough, especially about the future
All risk calculators—not just for anticoagulation—are based on the “average” patient. And no patient is average.
- How can I predict bleeding in my elderly patient taking anticoagulants?
We have tools, but their predictive value is modest. Clinical judgment is important.
- Zika—a new continent and new complications?
Zika reminds us that we live in a medically connected global community.
- Zika virus: A primer for clinicians
Zika is worrisome because of associations with microcephaly and Guillain-Barré syndrome. Watch for updates at cdc.gov.
- Drugs that may harm bone: Mitigating the risk
The implicated drugs have important therapeutic roles, so their benefits must be weighed against the risks.