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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Hospice & Palliative Medicine

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    Psychedelics in the medical toolbox?
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 200-201; DOI: https://doi.org/10.3949/ccjm.92b.04025

    Given the historical association of psychedelics as “recreational” mind-altering compounds within countercultures of the 1960s and 1970s, their current introduction into several aspects of medical practice is a surprise to many.

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    Psychedelics, spirituality, and existential distress in patients at the end of life
    Nicole Cornish, PharmD, Tara Coles, MD, M. Jennifer Cheng, MD, Claudia Ruiz Sotomayor, MD, DBe, Aaron Wolfgang, MD and Christopher Spevak, MD, MPH, JD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 248-254; DOI: https://doi.org/10.3949/ccjm.92a.24100

    The authors explore the role of psychedelics in addressing patients’ spiritual and existential suffering at the end of life from a medical, ethical, and legal perspective.

  • You have access
    Providing comfort: Caring for patients who wish to die in their home country
    Kelly Ferraro, MD, Sandhya Sharma, MD and Kimberly A. Indovina, MD
    Cleveland Clinic Journal of Medicine May 2024, 91 (5) 270-272; DOI: https://doi.org/10.3949/ccjm.91a.23095

    The authors offer a framework for providing equitable care to terminally ill patients who seek the comfort of dying at home.

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    Frequently asked questions about managing cancer pain: An update
    Renato V. Samala, MD, MHPE, FACP, FAAHPM, Ruth L. Lagman, MD, MPH, MBA, FACP, FAAHPM, Sina Najafi, DO and Flannery Fielding, CNP, MSN
    Cleveland Clinic Journal of Medicine March 2021, 88 (3) 183-191; DOI: https://doi.org/10.3949/ccjm.88a.20107

    Pain management can involve pharmacologic and nonpharmacologic therapies.

  • You have access
    Gastric outlet obstruction: A red flag, potentially manageable
    Andree H. Koop, MD, William C. Palmer, MD and Fernando F. Stancampiano, MD
    Cleveland Clinic Journal of Medicine May 2019, 86 (5) 345-353; DOI: https://doi.org/10.3949/ccjm.86a.18035

    Presume the cause to be a malignant tumor untill proven otherwise.

  • You have access
    Managing malignant pleural effusion
    Ali Saeed Wahla, MBBS, Mateen Uzbeck, MBBS, Yaser Abu El Sameed, MBBS and Zaid Zoumot, MBBS, MRCP, MSC, PHD
    Cleveland Clinic Journal of Medicine February 2019, 86 (2) 95-99; DOI: https://doi.org/10.3949/ccjm.86a.17095

    Depending on the circumstances, options are observation, thoracentesis, an indwelling catheter, and chemical pleurodesis.

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    A physician’s response to observational studies of opioid prescribing
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine November 2018, 85 (11) 824-825; DOI: https://doi.org/10.3949/ccjm.85b.11018

    Not long ago, we were told we needed to do better at relieving pain.

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    Severely frail elderly patients do not need lipid-lowering drugs
    Laurie Herzig Mallery, MD, FRCPC, MSM, Paige Moorhouse, MD, MPH, FRCPC, MSM, Pam McLean Veysey, BSc (Pharm), Michael Allen, MD, MSc and Isobel Fleming, BScPharm, ACPR
    Cleveland Clinic Journal of Medicine February 2017, 84 (2) 131-142; DOI: https://doi.org/10.3949/ccjm.84a.15114

    Statins have no role as primary prevention in this population, and a minor role as secondary prevention.

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    Statin therapy in the frail elderly: A nuanced decision
    Donald Clark, MD and Leslie S. Cho, MD
    Cleveland Clinic Journal of Medicine February 2017, 84 (2) 143-145; DOI: https://doi.org/10.3949/ccjm.84a.16036

    Clinicians—and patients—may reasonably feel there is value in statin therapy—even in advanced frailty.

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    Opioid therapy and sleep apnea (June 2016)
    Aaron S. Geller, MD
    Cleveland Clinic Journal of Medicine February 2017, 84 (2) 91-94; DOI: https://doi.org/10.3949/ccjm.84c.02001

    Readers comment on opioids and sleep apnea (June 2016).

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