Endocrinology
- SGLT-2 inhibitors are potential game-changers (for more than diabetes)
Data from large clinical trials and improved understanding of the biologic effects of these drugs are changing expectations for the clinical course in patients with diabetes, as well as chronic kidney disease and heart failure.
- SGLT-2 inhibitors in heart failure: Time for broader eligibility and earlier initiation
SGLT-2 inhibitors remain vastly underused in clinical practice despite their broad cardiorenal benefits.
- DXA and clinical challenges of fracture risk assessment in primary care
Overdependence on dual-energy x-ray absorptiometry, especially for patient populations the test was not designed for, may lead to poor clinical decisions.
- Elevated hCG can be a benign finding in perimenopausal and postmenopausal women
A search for the source of the elevation in perimenopausal and postmenopausal women who are not pregnant and have no disease or tumor may delay patient care.
- Ketogenic diets in the management of type 1 diabetes: Safe or safety concern?
A review of the potential risks and benefits for managing type 1 diabetes based on available evidence.
- Leriche syndrome
Physical examination revealed pallor of the toes, cold extremities, dry skin, and absence of bilateral femoral pulses. The patient also disclosed erectile dysfunction.
- Teriparatide: Label changes and identifying patients for long-term use
The changes leave clinicians with the challenge of identifying appropriate patients.
- Autoimmune brain disease: Think before testing
Immune serologic tests are not specific for any defined clinical diagnosis and thus should not be used to drive therapeutic decisions.
- How do you effectively evaluate the elderly for alcohol use disorder?
A brief review of clues to an underrecognized and underdiagnosed problem with physical as well as emotional and social consequences.
- Antiobesity drug therapy: An individualized and comprehensive approach
As part of a comprehensive plan, these drugs can provide lasting obesity control and additional health benefits, including decreased cardiovascular risk.

