Oncology

  • A brownish erythematous patch in the nipple-areola complex
    Irene López Riquelme, MD, Elisabeth Gómez Moyano, MD, PhD, María Ayala Blanca, PhD and Leandro Martínez Pilar, MD, PhD
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 241-242; DOI: https://doi.org/10.3949/ccjm.89a.21059

    Biopsy revealed neoplastic cells throughout the epidermis and granular layer, with abundant pale cytoplasm, intraglandular extension, and chronic inflammation in the papillary dermis.

  • Palliative care: An update for internists
    Rachel D. Havyer, MD, FAAHPM, Nauzley Abedini, MD, MSc, Robert L. Jayes, MD, Brenda Matti-Orozco, MD, Daniel H. Pomerantz, MD, MPH and Aziz A. Ansari, DO, SFHM, FAAHPM, FACP
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 262-268; DOI: https://doi.org/10.3949/ccjm.89a.21075

    A review of recent research to guide symptom management, advance-care planning, and communication training to maximize compassionate care.

  • Esophageal adenocarcinoma: A dire need for early detection and treatment
    Esophageal adenocarcinoma: A dire need for early detection and treatment
    Abel Joseph, MD, Siva Raja, MD, PhD, Suneel Kamath, MD, Sunguk Jang, MD, Daniela Allende, MD, Mike McNamara, MD, Gregory Videtic, MD, Sudish Murthy, MD and Amit Bhatt, MD
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 269-279; DOI: https://doi.org/10.3949/ccjm.89a.21053

    A clinical overview focused on screening, multidisciplinary evaluation, and treatment of early esophageal adenocarcinoma.

  • Treating anemia: It’s not just the EPO
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 174-175; DOI: https://doi.org/10.3949/ccjm.89b.04022

    Long-term effects of treatment with the new oral inhibitors of prolyl hydroxylase will need to be carefully monitored, as prolyl hydroxylase is a key structural component of diverse proteins.

  • Capsule endoscopy in gastrointestinal disease: Evaluation, diagnosis, and treatment
    Basil Akpunonu, MD, Jeannine Hummell, CNP, Joseph D. Akpunonu and Shahab Ud Din, MD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 200-211; DOI: https://doi.org/10.3949/ccjm.89a.20061

    The procedure is mainly used to evaluate obscure bleeding in the small bowel, but it is also used in the evaluation and diagnosis of a wide range of gastrointestinal conditions.

  • Anemia of chronic kidney disease: Will new agents deliver on their promise?
    Anemia of chronic kidney disease: Will new agents deliver on their promise?
    Tarek Souaid, MD, Jonathan Taliercio, DO, James F. Simon, MD, MBA, Ali Mehdi, MD, MEd and Georges N. Nakhoul, MD, MEd
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 212-222; DOI: https://doi.org/10.3949/ccjm.89a.21100

    A review of the pathophysiology of anemia of chronic kidney disease, major clinical trials, and novel therapies.

  • Microangiopathic hemolytic anemia in a female patient with systemic lupus erythematosus
    Mohammad A. Sohail, MD, Peter Luong, John Sedor, MD and Roop Kaw, MD
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 130-138; DOI: https://doi.org/10.3949/ccjm.89a.21066

    Evaluation of a patient presenting with worsening swelling of the lips and legs, decreased oral intake, intermittent pleuritic chest pain, and exertional dyspnea.

  • Breast cancer risk evaluation for the primary care physician
    Christine L. Klassen, MD, Elizabeth Gilman, MD, Aparna Kaur, MD, Sara P. Lester, MD and Sandhya Pruthi, MD
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 139-146; DOI: https://doi.org/10.3949/ccjm.89a.21023

    The authors offer a systematic approach to the assessment and management of patients at risk of breast cancer.

  • Soft tissue sarcoma: Recognizing a rare disease
    Amir Hossain Gahanbani Ardakani, BSc, MBBS, Alex Woollard, BM, BSc, PhD, FRCS (Plast), Howard Ware, MBBS, FRCS (Tr&Orth) and Panagiotis Gikas, MBBS Hons, MD (Res), PhD, FRCS (Tr&Orth)
    Cleveland Clinic Journal of Medicine February 2022, 89 (2) 73-80; DOI: https://doi.org/10.3949/ccjm.89a.21078

    Awareness of the signs and symptoms ensures prompt referral to a sarcoma center for appropriate assessment and treatment to optimize outcomes.

  • Recurrent anemia in a patient with chronic lymphocytic leukemia
    Sassine Ghanem, MD and Jason Gonsky, MD, PhD
    Cleveland Clinic Journal of Medicine February 2022, 89 (2) 91-98; DOI: https://doi.org/10.3949/ccjm.89a.21025

    New episodes of anemia do not automatically imply disease progression, and each should be evaluated completely.

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