Infectious Diseases

  • The gift of lasting immunity
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 263-264; DOI: https://doi.org/10.3949/ccjm.92b.05025

    Measles vaccine–induced immunity, although not necessarily lifelong for all individuals, is quite durable.

  • Does my adult patient need a measles vaccine?
    Kaitlyn R. Rivard, PharmD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 279-282; DOI: https://doi.org/10.3949/ccjm.92a.25038

    Possibly. Adults without acceptable presumptive evidence of immunity to measles should receive 1 dose of the measles-mumps-rubella vaccine, and 2 doses are recommended for adults in special situations.

  • Cardiovascular disease in people living with HIV: Risk assessment and management
    Elizabeth Ghandakly, MD, JD, Rohit Moudgil, MD, PhD and Katherine Holman, MD
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 159-167; DOI: https://doi.org/10.3949/ccjm.92a.24055

    Because people living with HIV develop coronary artery disease much earlier than the general population, careful attention must be given to assessment and management of their cardiovascular risk.

  • Heart to heart: Progress in cardiovascular disease prevention for people living with HIV
    James Hekman, MD and Henry H. Ng, MD, MPH
    Cleveland Clinic Journal of Medicine March 2025, 92 (3) 168-170; DOI: https://doi.org/10.3949/ccjm.92a.24126

    The already higher cardiovascular risk in people living with HIV is exacerbated by social determinants of health such as socioeconomic status, access to healthcare, and systemic discrimination. Interventions that address this risk must be based in medical science and equity.

  • Which patients with presumed acute infectious diarrhea in an outpatient setting should undergo gastrointestinal pathogen panel testing?
    Brittany Jackson, MD, Sabrina Billings, MD, Dana M. Harris, MD, Jane Hata, PhD and Mary S. Hedges, MD
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 83-86; DOI: https://doi.org/10.3949/ccjm.92a.24084

    Use of a gastrointestinal pathogen panel is warranted in certain individuals, such as those with fever, visible blood in the stool, sepsis, or a compromised immune system.

  • Respiratory virus season: Strategies for successful navigation
    Pooja Cerrato, PharmD, BCPS and Steven Mawhorter, MD, DTM&H
    Cleveland Clinic Journal of Medicine February 2025, 92 (2) 95-102; DOI: https://doi.org/10.3949/ccjm.92a.24103

    The authors review the burden, prevention, diagnosis, and treatment of influenza, COVID-19, and respiratory syncytial virus infection.

  • How can I better recognize and manage delirium in my hospitalized patients?
    Amanda Pomerantz, DO, Anna P. Shapiro-Krew, MD and Andrew Coulter, MD, MA
    Cleveland Clinic Journal of Medicine January 2025, 92 (1) 17-20; DOI: https://doi.org/10.3949/ccjm.92a.24048

    By knowing common precipitants and mimickers of delirium and considerations for workup, clinicians can implement nonpharmacologic preventive strategies, better identify patients experiencing delirium, and optimize symptom management.

  • Shortness of breath in a 52-year-old man with HIV and severe mitral regurgitation
    Felix Wangmang, MD, PharmD, Achilles Aiken, MD and Kuang-Yuh Chyu, MD, PhD
    Cleveland Clinic Journal of Medicine January 2025, 92 (1) 23-30; DOI: https://doi.org/10.3949/ccjm.92a.24060

    The patient presented with 3 weeks of acute on chronic dyspnea on exertion with progression to dyspnea at rest and associated orthopnea.

  • Oral condylomata lata
    Carine J. Moezinia, MBBS, MD, Benjamin P. Zuckerman, MBBS and Ayeshah Abdul-Hamid, MBChB
    Cleveland Clinic Journal of Medicine December 2024, 91 (12) 725-726; DOI: https://doi.org/10.3949/ccjm.91a.24045

    The patient had a 3-month history of painless oral lumps and intermittent sore throat.

  • Matter of the heart: Prioritizing harm reduction in managing infective endocarditis associated with injection drug use
    Akhil Anand, MD, Jared Ontko, Jyothika Yermal, Kush Sehgal, MBBS and Ashley Cantu-Weinstein, MD
    Cleveland Clinic Journal of Medicine December 2024, 91 (12) 731-734; DOI: https://doi.org/10.3949/ccjm.91a.24020

    Despite specialty society recommendations, many patients do not receive treatment for substance use disorder in conjunction with heart disease treatment.

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