topic

  • We have a greater understanding of ‘cardiac syndrome X,’ but questions remain
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 532-533; DOI: https://doi.org/10.3949/ccjm.88b.10021

    A better understanding of angina due to ischemia and no obstructive coronary artery disease has led to recognition of coronary microvascular dysfunction in many of these patients.

  • Revisiting the ‘great masquerader’
    Raihan Ashraf, MD, Rahul Mahajan, MD, Debajyoti Chatterjee, DM and Kollabathula Arpitha, MD
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 536-537; DOI: https://doi.org/10.3949/ccjm.88a.20203

    An HIV patient presents with scaly brown lesions on the palms and soles, mildly painful oral erosions, and a buzzing sound in the right ear for the past 20 days.

  • Chest pain: The importance of serial ECGs
    Rene Jansen van Rensburg, MBChB, MD, Jason Schutte, MBChB and Thomas de Beenhouwer, MD
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 538-540; DOI: https://doi.org/10.3949/ccjm.88a.20183

    Repeat electrocardiograms in a 44-year-old man who presented with severe hypertension revealed de Winter and Wellens patterns.

  • Fungus among us: A poster child for diagnostic stewardship
    Sherif Beniameen Mossad, MD, FACP, FIDSA, FAST
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 541-542; DOI: https://doi.org/10.3949/ccjm.88a.21065

    When interpreting the significance of Aspergillus species in respiratory culture, first ask if the culture was clinically indicated, or if this was an incidental finding.

  • Is Aspergillus isolated from respiratory cultures clinically significant?
    Firas El-Baba, MD, Donovan Watza, PhD and Ayman O. Soubani, MD
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 543-546; DOI: https://doi.org/10.3949/ccjm.88a.20188

    Aspergillus is ubiquitous, so the significance of the finding depends on the patient’s symptoms, underlying lung condition, immune status, and radiologic fi ndings.

  • Ketogenic diets in the management of type 1 diabetes: Safe or safety concern?
    Lauren Anne Buehler, MD, MPH, Dawn Noe, RDN, LD, CDCES, Shannon Knapp, BSN, RN, CDCES, Diana Isaacs, Pharm D, CDCES and Kevin M. Pantalone, DO, ECNU, FACE
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 547-555; DOI: https://doi.org/10.3949/ccjm.88a.20121

    A review of the potential risks and benefits for managing type 1 diabetes based on available evidence.

  • Risk-based guidelines: Redefining management of abnormal cervical cancer screening results
    Amy Wiser, MD, FAAFP, Jeffrey D. Quinlan, MD, FAAFP and Pelin Batur, MD, FACP, NCMP
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 556-560; DOI: https://doi.org/10.3949/ccjm.88a.20193

    A shift from results-based to risk-based management, based on the patient’s immediate and 5-year risks of grade 3 or higher cervical intraepithelial neoplasia.

  • Coronary microvascular dysfunction: Considerations for diagnosis and treatment
    Coronary microvascular dysfunction: Considerations for diagnosis and treatment
    Benita Tjoe, MD, Lili Barsky, MD, Janet Wei, MD, Bruce Samuels, MD, Babak Azarbal, MD, C. Noel Bairey Merz, MD and Chrisandra Shufelt, MD, MS
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 561-571; DOI: https://doi.org/10.3949/ccjm.88a.20140

    A review of pathophysiology, considerations for invasive and noninvasive coronary function testing, management, and remaining knowledge gaps.

  • Rapid cognitive decline and myoclonus in a 52-year-old woman
    William Gravley, MS, Caleb Murphy, MD, MBA, Chia-Dan Kang, MD and Badrunnisa Hanif, MD
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 572-583; DOI: https://doi.org/10.3949/ccjm.88a.20004

    Symptoms also included confusion, blank staring, blurred vision, incoordination of the extremities, decreased verbal communication, and holding her left hand in a fist.

  • The initial viral infection may be only part of the story
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine September 2021, 88 (9) 476-477; DOI: https://doi.org/10.3949/ccjm.88b.09021

    We clearly see that the coronavirus elicits syndromes far afield from respiratory tissues. But a virus eliciting effects seemingly distinct from the primary infection is nothing new.

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