topic
- Widespread skin-thickening and hyperpigmentation
A 37-year-old military veteran presented with extensive velvety hyperpigmented plaques over nearly 15% of the total body surface.
- Phenytoin-induced gingival overgrowth
A young man presented with lower-extremity weakness and slurred speech. He has been on seizure prophylaxis after experiencing a seizure following hemicraniectomy for subdural hematoma.
- Mucinous ascites: Pseudomyxoma peritonei
A 59-year-old man presented with progressive abdominal distention that limited daily activities and oral intake. The ascitic fluid was markedly viscous and jelly-like.
- Nasal herpes simplex virus infection
Skin changes on the nose in a 37-year-old patient that began after a scratch were concerning for extensive nasal skin necrosis.
- Hyperpigmentation as a clue to Addison disease
The 66-year-old woman presented with fatigue, loss of appetite, and hyperpigmentation of the tongue, soft palate, buccal mucosa, lower lip, fingers, and nail beds.
- Diversifying medical humanities: The case for Jay-Z
Physicians carry considerable power in the patient-physician relationship. Opening our minds to the viewpoints of others diffuses some of that power and grounds us in the communities we serve.
- Steroids in the acutely ill: Evolving recommendations and practice
New information has been generated with regard to what causes critical illness-related corticosteroid insufficiency, how to diagnose it, who should receive corticosteroid treatment, and what regimens to use.
- Primary and secondary prevention of atherosclerotic cardiovascular disease: A case-based approach
The authors present commonly encountered clinical scenarios that pose challenges in decision-making in primary and secondary prevention.
Cirrhotic coagulopathy: A rebalanced hemostasisCirrhosis affects all 3 phases of coagulation, leading to a delicate new equilibrium, easily disturbed and tipped toward either bleeding or thrombosis by acute events such as infection, renal failure, and invasive procedures.
- Circulating lipids are not all bad: An LDL mimic that may be only skin deep
Although lipoprotein-X separates out by density in the low-density lipoprotein (LDL) fraction and thus may appear as LDL in the laboratory report, it is biologically unique.